[Beta 2-microglobulin test in the diagnosis of chronic kidney diseases]

A study was made of the content of low molecular protein B2-microglobulin in the blood and urine of 126 patients with chronic renal diseases and 95 healthy persons. As a result of the study it was shown that B2-microglobulin concentration in the blood grows with age. The maximum level of B2-microglobulin was marked in patients with chronic glomerulonephritis. A high level of the urinary excretion of B2-microglobulin with a moderate rise of its concentration in the blood is typical of patients with chronic pyelonephritis during exacerbation. Indices of the B2-microglobulin test are closely related to renal function. The B2-microglobulin test is of great diagnostic significance as it provides an opportunity to establish the nature of proteinuria, site and expression of renal pathologic processes.