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Updated: Jul 14, 2026

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons
Published on: November 14, 2018
Sunflower Pollen-Derived Microspheres Selectively Absorb DNA for microRNA Detection
Yao Yang1, Ziye Mou2, Qian Liu3
1Institute of Respiratory Diseases, Xinqiao Hospital, Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Third Military Medical University, Chongqing, 400037, China.
Abstract:
Herein, we report the finding that a naturally sunflower pollen-derived microspheres (HSECs) with hierarchical structures can selectively absorb polyC and polyA with high efficiency and affinity. HSECs exhibit the capability to selectively absorb polyC and polyA ssDNA under neutral and acidic conditions. It has been observed that the presence of metal cations, specifically Ca2+, enhances the absorption efficiency of HSECs. Mechanically, this absorption phenomenon can be attributed to both electrostatic interactions and cation-π interactions. Such an appealing property enables the functionalization of HSECs for broad potential biomedical applications, such as microRNA detection.

