Related Experiment Video
Updated: Jun 24, 2025

06:41
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
9.0K
Recent Progress in Hair Science and Trichology
1Shiseido Co., Ltd. MIRAI Technology Institute.
Journal of Oleo Science
|June 2, 2024
Summary
This review summarizes recent advances in understanding human hair structure and the distribution of active ingredients. It also explores hair's potential as a substrate for flexible electronic devices.
Area of Science:
- Biophysics
- Materials Science
- Cosmetic Science
Background:
- Human hair is vital for appearance and protection, primarily composed of proteins, pigments, water, and lipids.
- Despite over a century of study, the physicochemical properties of hair remain incompletely understood.
- Recent research offers new insights into hair's structure, ingredient delivery, and novel applications.
Purpose of the Study:
- To review recent progress in understanding hair's structural characteristics.
- To summarize findings on the delivery and distribution of active ingredients within hair.
- To introduce the emerging potential of hair as a substrate for flexible device fabrication.
Main Methods:
- Microscopic and spectroscopic techniques, including Atomic Force Microscopy-Infrared Spectroscopy (AFM-IR), were used to investigate structural characteristics.
- Rheological measurements provided further insights into hair's physical properties.
- Nanoscale Secondary Ion Mass Spectrometry (NanoSIMS) was employed to evaluate the distribution of active ingredients.
Main Results:
- Advanced techniques like AFM-IR and rheology have enhanced the understanding of hair's complex structure.
- NanoSIMS has enabled detailed mapping of active ingredient distribution within hair.
- Emerging research highlights hair's unique properties for potential use in flexible electronics.
Conclusions:
- A deeper understanding of hair's physicochemical properties has been achieved through recent advancements.
- The study of active ingredient delivery and distribution in hair has been significantly refined.
- Hair presents a promising, sustainable biomaterial for future technological applications, including flexible devices.
Related Concept Videos
Multipotency and Niche of Bulge Stem Cell
3.6K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.6K
Confocal Fluorescence Microscopy
13.2K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.2K
Clinical Applications of Epidermal Stem Cells
2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K

