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Related Experiment Video

Updated: Jun 24, 2025

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Published on: November 4, 2021

Systemic embolization in infective endocarditis.

Henrik Agerup Kildahl^1,2, Evelyn Lauvstad Brenne¹, Håvard Dalen^2,3

¹Department of Cardiothoracic Surgery, St Olavs Hospital, Trondheim, Norway.

Indian Journal of Thoracic and Cardiovascular Surgery

|June 3, 2024

Summary

This summary is machine-generated.

Embolism is a frequent complication of infective endocarditis (IE), impacting 20-40% of patients. While surgery reduces embolism risk, the benefit of treating asymptomatic embolism remains unclear.

Keywords:

Cardiothoracic surgery Infective endocarditis Systemic embolization

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Area of Science:

Cardiology
Infectious Diseases
Neurology

Background:

Embolism is a significant complication of infective endocarditis (IE), leading to severe outcomes like stroke and ischemia.
Large registries indicate 20-40% of IE patients experience embolism, often at diagnosis.

Purpose of the Study:

To investigate the incidence of embolism in infective endocarditis patients.
To evaluate the rate of embolism during hospitalization and post-surgery.
To assess the clinical significance of asymptomatic embolism in relation to surgical treatment.

Main Methods:

A comprehensive literature search was conducted.
A retrospective analysis of 390 infective endocarditis cases diagnosed between 2010 and 2020 at a single center was performed.

Main Results:

The rate of embolism during hospitalization was 11%, with only 2% developing embolism during or after surgery.
Routine imaging identified asymptomatic cerebral embolism in 8.5% of patients undergoing surgery.
Guidelines suggest surgery for IE with prior embolism or vegetations >10 mm.

Conclusions:

While surgery appears to reduce the risk of embolism during or after the procedure, its impact on overall prognosis needs further investigation.
The clinical utility of detecting and treating asymptomatic embolism in infective endocarditis patients remains uncertain.