Evolution of the Push-2-Spin Fat Graft Processing Device: Enhancing Efficiency and Reducing Risk of Contamination

Area of Science:

• Aesthetic surgery
• Regenerative medicine
• Biomaterials

Background:

• Small-volume fat grafting efficiency is crucial for cost-effectiveness in aesthetic procedures.
• The Push-2-Spin (P2S) system offers a rapid, handheld solution to improve fat grafting processes.
• Previous iterations aimed to minimize operative time and mess in fat processing.

Purpose of the Study:

• To introduce technical innovations to the P2S prototype for enhanced operative ease, speed, and safety.
• To compare the efficacy and viability of fat processing using the P2S handheld (P2S-H) device against other methods.
• To assess the risk of contamination with different fat processing techniques.

Main Methods:

• Lipoaspirate from abdominoplasty samples was processed using centrifugation, gauze rolling, mesh straining, tabletop P2S, and P2S-H.
• Evaluated operative processing time, spin time, oil fraction, stromal vascular fraction (SVF) yield and viability, and adipocyte viability.
• Assessed contamination risk via blood agar smears of lipoaspirate.

Main Results:

• The P2S-H device demonstrated superior speed compared to its previous version and other techniques.
• Inline processing with the P2S-H system significantly reduced contamination risk compared to open-air methods.
• Oil yield, adipocyte, and SVF number and viability remained consistent across all tested techniques.

Conclusions:

• Technical advancements in the P2S system, particularly the handheld unit, improve operative efficiency and reduce space requirements.
• These improvements enhance the surgeon's quality of life without negatively impacting fat extraction efficacy, cellular yield, or cell viability.
• The P2S-H system represents a significant advancement in fat processing for aesthetic fat grafting.