Related Experiment Video
Updated: Jun 24, 2025
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.0K
[Acute ischemic stroke and troponin elevation: update of the Mannheim clinical algorithm]
Louisa Becker1, Angelika Alonso1, Mathieu Kruska2
1Neurologische Klinik, Universitätsmedizin Mannheim (UMM) und Mannheim Center for Translational Neurosciences (MCTN), Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Deutschland.
Innere Medizin (Heidelberg, Germany)
|June 3, 2024
Summary
About half of acute ischemic stroke (AIS) patients have elevated high-sensitivity cardiac troponin (hs-cTn) levels, increasing cardiac risks. A standardized algorithm and expert collaboration are crucial for diagnosing diverse causes of troponin elevation in AIS.
Area of Science:
- Cardiology
- Neurology
- Biochemistry
Context:
- Elevated high-sensitivity cardiac troponin (hs-cTn) is common in acute ischemic stroke (AIS).
- These patients face increased risks of morbidity and mortality, often cardiac-related.
- Identifying the cause of hs-cTn elevation is critical for appropriate management.
Purpose:
- To present a practice-oriented approach for the differential diagnosis of hs-cTn elevation in AIS patients.
- To update the Mannheim clinical algorithm for managing troponin elevation in acute ischemic stroke.
- To emphasize the need for a multidisciplinary approach involving cardiologists and neurologists.
Summary:
- Approximately 50% of AIS patients exhibit elevated hs-cTn levels.
- Most hs-cTn elevations in AIS are due to non-ischemic myocardial injury.
- Causes are diverse, sometimes silent, and can include life-threatening conditions like myocardial infarction.
Impact:
- Facilitates accurate diagnosis and timely intervention for cardiac complications in AIS.
- Improves patient outcomes by guiding appropriate work-up and treatment strategies.
- Provides a standardized clinical algorithm for healthcare professionals managing AIS patients with elevated troponin.
