[Treatment of hypertension in the diabetic with captopril]

The apparently excellent pharmacological properties of Captopril as treatment for insulin-dependent and other hypertensive diabetics of all ages were investigated at a Diabetes Centre. Fifteen out-patients receiving oral hypoglycaemic drugs or insulin and suffering from slight or moderate hypertension (diastolic AP: 95-115 mmHg) were selected for treatment. The Captopril was administered in daily doses of 50 or 100 mg for 60 days. Tests on the 30th and 60th days revealed a statistically significant reduction in max/min OAP values, but no statistically significant variations in either cardiac frequency or glycaemia before and after meals. Nor did the main haematochemical parameters show any significant alteration.