Related Experiment Video

Updated: Jun 24, 2025

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay
08:56

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay

Published on: May 5, 2020

5.9K

Correction: Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction.

Amanda E Siglin, Shangjin Sun, Jeffrey K Moore

    Plos One
    |June 4, 2024
    PubMed
    Summary

    This study corrects a previous article DOI. The correction ensures accurate citation and retrieval of scientific research for better accessibility.

    More Related Videos

    Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry14:47

    Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

    Published on: May 17, 2016

    9.8K
    Production of Dynein and Kinesin Motor Ensembles on DNA Origami Nanostructures for Single Molecule Observation08:09

    Production of Dynein and Kinesin Motor Ensembles on DNA Origami Nanostructures for Single Molecule Observation

    Published on: October 15, 2019

    6.6K

    Related Concept Videos

    Microtubule Associated Motor Proteins01:32

    Microtubule Associated Motor Proteins

    Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they associate with, the direction they move within the cell, and the type of cargo they transport. Motor proteins that associate with microtubules are known as microtubule-associated motor proteins. There are two families of microtubule-associated motor proteins —Kinesins and Dyneins. Both these proteins assist in the transport of cellular...
    7.9K
    The Movement of Organelles and Vesicles01:43

    The Movement of Organelles and Vesicles

    In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
    4.4K
    Cytoskeletal Accessory Proteins01:13

    Cytoskeletal Accessory Proteins

    The cytoskeleton is an essential cell component that plays several structural and functional roles. However, the filaments that make up the cytoskeleton cannot function independently and depend on the accessory or ancillary proteins to effectively carry out their function. Accessory proteins associate with cytoskeletal filaments and their monomers, aiding filament formation and function. They also help in the cross-communication among cytoskeletal filaments. Cytoskeletal accessory proteins are...
    3.0K
    Disassembly of Intermediate Filaments01:35

    Disassembly of Intermediate Filaments

    Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to regulate their disassembly. The IF concentration in the cytoplasm also regulates the disassembly. If the concentration crosses a threshold, it activates the protein kinases in the vicinity, allowing the phosphorylation of IFs.
    Keratin proteins, found at the cell periphery near cell junctions, undergo a cycle of assembly and disassembly. In Type...
    2.1K
    Attachment of Sister Chromatids02:57

    Attachment of Sister Chromatids

    As cells progress into mitosis, the nuclear envelope breaks down, and the condensed chromosomes are exposed to the array of bipolar microtubules of the mitotic spindle. The kinetochore, a large, disc-shaped protein complex, is present at the centromere region of the sister chromatids and acts as a binding site for the microtubules.  Usually, the plus-end of a single microtubule is embedded within the kinetochore. However, some kinetochores first establish lateral contact with the side-wall...
    3.3K
    Pinching-off of Coated Vesicles01:32

    Pinching-off of Coated Vesicles

    Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
    3.1K