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Hybrid Ethylcellulose Polymeric Films: Ag(I)-Based Components and Curcumin as Reinforcing Ingredients for Enhanced
Alessandra Crispini1, Iolinda Aiello1,2,3, Nicolas Godbert1,2
1MAT-InLAB, LASCAMM CR-INSTM, Unità INSTM della Calabria, Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, 87036, Arcavacata di Rende, CS, Italy.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|June 5, 2024
Summary
Bio-active ethylcellulose (EC) films incorporating curcumin and silver compounds exhibit antimicrobial properties. The EC films containing silver show good performance against Staphylococcus aureus with minimal silver release.
Area of Science:
- Materials Science
- Polymer Chemistry
- Nanotechnology
Background:
- Ethylcellulose (EC) is a versatile polymer matrix.
- Curcumin (curc) possesses antioxidant properties.
- Silver (Ag(I))-based compounds are known for their antimicrobial activity.
Purpose of the Study:
- To develop bio-active ethylcellulose (EC) polymeric films.
- To incorporate curcumin (curc) and Ag(I)-based compounds into EC films.
- To evaluate the antimicrobial activity and silver migration of the developed films.
Main Methods:
- Solvent casting method for film preparation.
- Characterization using Powder X-Ray Diffraction (PXRD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared (FTIR) spectroscopy, Scanning Electron Microscope (SEM), and UV-vis spectroscopy.
- Antimicrobial tests and Silver migration tests.
Main Results:
- The developed EC films incorporated curcumin and Ag(I)-based compounds.
- Characterization revealed the non-inert behavior of EC with the active ingredients.
- Antimicrobial tests demonstrated good performance against Staphylococcus aureus.
- Silver migration tests showed low silver release, especially from EC films with [(bpy)Ag(OTf)]∞-curc.
Conclusions:
- Bio-active EC films incorporating curcumin and Ag(I)-based compounds were successfully prepared.
- These hybrid films exhibit significant antimicrobial activity.
- The EC films containing Ag(I)-based compounds are promising for applications requiring antimicrobial properties with controlled silver release.
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