Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Spurious elevated platelet counts associated with bacteremia.

E S Gloster, R A Strauss, J F Jimenez

American Journal of Hematology

|March 1, 1985

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Is the type of neuraxial anesthesia associated with adverse neonatal outcomes among patients with preeclampsia?

Journal of neonatal-perinatal medicine·2019

Same author

Pitfalls in prenatal diagnosis of a fixed retroflexed fetal head.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2012

Same author

The Mansfield pre-service and in-service program.

American journal of mental deficiency·2010

Same author

Photolithographic mask alignment using moiré techniques.

Applied optics·2010

Same author

Small-angle diffusing screens for photolithographic camera illumination systems.

Applied optics·2010

Same author

Varifocal mirror technique for video transmission of three-dimensional images.

Applied optics·2010

Same journal

Clinical Predictors of Response in Chronic Graft-Versus-Host Disease: Results From the "Predicting the Quality of Response to Specific Treatments (PQRST)" Trial.

American journal of hematology·2026

Same journal

Relapse Thresholds (12/24 Mo) Define Survival Disparity in Pediatric B-ALL.

American journal of hematology·2026

Same journal

Quizartinib in Combination With FLAG-IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG-QUIDA): A PETHEMA Phase I-II Trial.

American journal of hematology·2026

Same journal

Defining a Subgroup of Myelodysplastic Syndrome Patients With Very Poor-Risk Cytogenetics Demonstrating a Relatively More Favorable Outcome After Allogeneic Hematopoietic Cell Transplantation.

American journal of hematology·2026

Same journal

Safety and Efficacy of Plerixafor in Poor Mobilizers With Lymphoma: A Multicenter, Prospective, Single-Arm Study.

American journal of hematology·2026

Same journal

Dordaviprone Maintenance After Allogeneic HCT for High-Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm.

American journal of hematology·2026

See all related articles

Bacteremia can cause falsely high automated platelet counts. Bacteria in blood samples interfere with laser optical counters, leading to inaccurate results.

Area of Science:

Hematology
Clinical Pathology
Medical Laboratory Science

Background:

Automated blood cell counters are crucial for accurate platelet counts.
In vivo bacteremia is a serious condition requiring prompt diagnosis.
Artifacts in automated counts can lead to misdiagnosis and delayed treatment.

Observation:

Two patients presented with bacteremia caused by Escherichia coli and Klebsiella pneumoniae.
Bacteria were observed on peripheral blood smears in both cases.
Automated platelet counts were spuriously elevated in these patients.

Findings:

The presence of bacteria in vivo led to falsely elevated platelet counts.
The Ortho ELT-8 laser optical counter generated these spurious results.

Related Experiment Videos

This represents a previously unreported artifact in automated hematology.

Implications:

Clinicians must be aware of potential artifacts in automated platelet counts during bacteremia.
Microscopic examination of blood smears is essential to confirm automated findings.
This highlights the need for critical evaluation of automated cell counter results in infectious states.