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Updated: May 11, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018
Giant cell-rich osteosarcoma of the lumbar spine - A rare entity
Tushar Kalekar1, Ojasvi Sharma1, Sayali Paidlewar1
1Department of Radiodiagnosis, Dr. DY Patil Medical College, Hospital and Research Centre, Pune, India.
Abstract:
Giant cell-rich osteosarcoma (GCRO) is a rare variant of osteosarcoma. A significant diagnostic hurdle is presented by the lesion's uncommon appearance on histopathology. This report presents a case of a 59-year-old female patient diagnosed with GCRO.
Contribution:
While it is extremely difficult to distinguish GCRO from malignant giant cell tumour, it is important to do so because of the difference in prognosis and management. Distinctive anatomy of the lumbar spine increases the risks associated with surgical excision.
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