Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Caroline Madsen1, Andreas Overby Ørsted2, Maria Birkvad Rasmussen3

  • 1Gynækologisk og Obstetrisk Afdeling, Københavns Universitetshospital - Rigshospitalet.

Ugeskrift for Laeger
|June 7, 2024
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic and treatment delay in women with cancer in pregnancy: a case-based study.

Archives of gynecology and obstetrics·2026
Same author

Pregnancy Outcomes in Women with Type 1 Diabetes by Socioeconomic and Mental Health Disadvantages.

Clinical epidemiology·2026
Same author

Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects.

Nature communications·2026
Same author

Gestational Diabetes Mellitus and Risk of Selected Cancers: A Danish National Register-based Cohort Study.

The Journal of clinical endocrinology and metabolism·2026
Same author

Birth weight of term born offspring in relation to long-term maternal cardiovascular morbidity and mortality.

European journal of epidemiology·2026
Same author

Temporal Trends in Pregnancy Outcomes Among Parents With Type 1 Diabetes: A Nationwide Register-Based Study.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Prophylactic vaginal progesterone can reduce early preterm birth in high-risk pregnancies. This treatment is recommended for women with a history of preterm birth or a short cervix.

Area of Science:

  • Obstetrics and Gynecology
  • Perinatology
  • Neonatal Health

Background:

  • Preterm birth (less than 37 weeks gestation) is a major global cause of infant mortality and morbidity.
  • While incidence varies, it is notably lower in Nordic countries (5-6%).
  • Predicting and preventing preterm birth is challenging due to its varied causes.

Purpose of the Study:

  • To review current knowledge on the use of prophylactic progesterone to prevent preterm birth.
  • To identify high-risk pregnancies that may benefit from progesterone therapy.
  • To provide guidance on the optimal timing and indications for progesterone administration.

Main Methods:

  • Review of existing scientific literature on prophylactic progesterone and preterm birth.
  • Analysis of factors influencing preterm birth prediction, including obstetric history and cervical length.

Related Experiment Videos

  • Evaluation of treatment recommendations based on gestational age and risk factors.

    • Main Results:

    • Obstetric history and cervical length measurements can improve the prediction of preterm birth.
    • Prophylactic vaginal progesterone, given between 12-24 weeks gestation, is recommended for singleton pregnancies with a history of preterm birth or a short cervix (less than 25 mm).
    • This intervention is associated with a reduction in preterm birth before 33-35 weeks gestation.

    Conclusions:

    • Vaginal progesterone is an effective prophylactic measure for specific high-risk singleton pregnancies.
    • Consideration should be given to using progesterone in twin pregnancies with similar risk factors.
    • Early intervention with progesterone can significantly reduce the incidence of early preterm birth and associated neonatal complications.