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Updated: Jun 24, 2025

Author Spotlight: Investigating Wound Healing in Mice Models of Oronasal Fistulas
Published on: September 8, 2023
Waiting for self-healing as a primary management strategy for lower lip mucoceles
Jian-Lin Liu1, Yu-Nan Liu2, Lin Wang2
1Department of Stomatology, Liaocheng People's Hospital, 67 Dongchan West Road, Dongchang District, Liaocheng City, Shandong, 252000, PR China.
Objectives:
Oral mucoceles are most frequently encountered on the lower lip. A variety of treatment options are currently employed, including surgical excision, pharmacological injections, and laser therapy. However, each of these approaches may introduce risks and potential complications. Clinical practice has demonstrated a potential for self-healing in lower lip mucoceles, making a conservative observational approach more appealing. This research is a prospective study aimed at evaluating the self-healing capacity of lower lip mucoceles.
Methods:
In this prospective study, patients with mucoceles were encouraged to intentionally delay medical intervention and to wait for self-healing. Disappearance of the mucocele for at least 3 months was defined as self-healing.
Results:
Thirty patients with lower lip mucoceles were included. With no intervention, 24 patients (80%) reported self-healing of lower lip mucoceles. The mean natural duration of the mucoceles was 3.63 (± 4.7; 1-24) months. After self-healing of the mucocele, the patients were followed up for 17.21 (± 9.45; 2-30) months and there were no reported recurrences.
Conclusions:
Lower lip mucoceles have a high potential for self-healing and patients may be routinely encouraged to wait for self-healing.
Clinical Relevance:
The high self-healing rate observed in this study suggests that a conservative, non-interventional approach might be considered as the first-line management for lower lip mucoceles.
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