Modified topical steroid therapy for the treatment of oral mucous membrane pemphigoid

A modified approach to the treatment of two patients with oral mucous membrane pemphigoid, using an adaptation of a custom fluoride carrier, is described. The method provided for occlusive topical steroid therapy, overcoming many of the obstacles to such treatment for oral lesions. Response was excellent, with no adverse local or systemic effects. Further clinical trials to determine the applicability of this form of therapy in the treatment of patients with a number of infectious, ulcerative, and vesiculobullous oral diseases appear warranted.