Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

2.7K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
2.7K
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

7.0K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
7.0K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

13.2K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cutting-edge advancements in biomaterials under the guidance of intelligence and bionics.

Regenerative biomaterials·2026
Same author

Highly stretchable and conformal bioinspired kirigami structural epidermal electrodes for ECG recording during daily activities.

Microsystems & nanoengineering·2026
Same author

Intelligent soft robotic gripper for non-destructive grasping and attribute recognition via multi-modal waveguide tactile sensors.

Microsystems & nanoengineering·2026
Same author

Hybrid calibration algorithm based on RKHS-PLSR for high-accuracy noninvasive optical monitoring of blood parameters.

Optics express·2026
Same author

Personalized non-invasive continuous glucose monitoring via multiparameter-informed machine learning.

Biosensors & bioelectronics·2026
Same author

High peak power sub-nanosecond 2.1 μm Raman generator.

Optics letters·2026

Related Experiment Video

Updated: Jun 24, 2025

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging
10:01

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

Published on: September 8, 2017

7.7K

Extended-depth-of-field imaging with an ultra-thin folded lens.

Lehan Zhang, Shuo Wang, Dachao Li

    Journal of the Optical Society of America. A, Optics, Image Science, and Vision
    |June 10, 2024
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces an ultra-thin annular folded lens (AFL) for compact extended depth of field (EDOF) imaging. The innovative lens design achieves a large depth of field (DOF) crucial for observation and measurement applications.

    More Related Videos

    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
    08:41

    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

    Published on: August 16, 2012

    11.5K
    Single Plane Illumination Module and Micro-capillary Approach for a Wide-field Microscope
    08:53

    Single Plane Illumination Module and Micro-capillary Approach for a Wide-field Microscope

    Published on: August 15, 2014

    9.7K

    Related Experiment Videos

    Last Updated: Jun 24, 2025

    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging
    10:01

    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

    Published on: September 8, 2017

    7.7K
    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
    08:41

    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

    Published on: August 16, 2012

    11.5K
    Single Plane Illumination Module and Micro-capillary Approach for a Wide-field Microscope
    08:53

    Single Plane Illumination Module and Micro-capillary Approach for a Wide-field Microscope

    Published on: August 15, 2014

    9.7K

    Area of Science:

    • Optics and Photonics
    • Optical Engineering
    • Imaging Systems

    Background:

    • Conventional optical elements face challenges in achieving compactness and extended depth of field (EDOF) for observation and measurement.
    • Miniaturization of imaging systems is critical for various applications, but often limited by optical design constraints.

    Purpose of the Study:

    • To propose and validate an innovative solution for miniaturized EDOF imaging systems.
    • To introduce an ultra-thin annular folded lens (AFL) as a novel optical element for enhanced depth of field (DOF).

    Main Methods:

    • Design of an annular four-folded lens with specific optical parameters (focal length, thickness).
    • Utilizing optical simulations to evaluate the depth of field (DOF) performance.
    • Development of an AFL-based test system for resolution and wavelength range assessment.

    Main Results:

    • The designed annular folded lens achieved a total thickness of 8.50 mm and an effective focal length of 80.91 mm.
    • Simulations demonstrated a substantial depth of field (DOF) of 380.55 m.
    • The AFL-based test system exhibited a resolution of 0.11 mrad over a broad wavelength range (486-656 nm).

    Conclusions:

    • The ultra-thin annular folded lens (AFL) offers a promising approach for miniaturizing extended depth of field (EDOF) imaging systems.
    • Experimental validation confirms the potential of AFLs for compact, long-range EDOF imaging applications.
    • This technology could significantly advance observation and measurement capabilities in space-constrained environments.