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Updated: Jun 24, 2025

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Published on: May 31, 2021
[Cow's milk allergy: diagnostic process. Expert consensus]
María Del Carmen Toca1, Claudio Parisi2, Adriana Fernández3
1Comité de Gastroenterología; Sociedad Argentina de Pediatría, Ciudad Autónoma de Buenos Aires, Argentina.
Cow's milk protein allergy in children presents diagnostic challenges due to varied mechanisms and clinical presentations. This consensus provides interdisciplinary recommendations for accurate diagnosis and comprehensive patient care.
Area of Science:
- Pediatric Allergy and Immunology
- Gastroenterology
- Neonatology
Context:
- Cow's milk protein allergy (CMPA) is a common food allergy in infants and children.
- Diagnosis is complicated by diverse clinical manifestations and varying onset during pediatric development.
- Risk of misdiagnosis (under- or over-diagnosis) necessitates standardized diagnostic approaches.
Purpose:
- To establish updated, interdisciplinary recommendations for the accurate diagnosis of cow's milk protein allergy.
- To synthesize current scientific evidence with expert clinical experience.
- To improve the diagnostic process and patient management.
Summary:
- Utilized the Delphi method, integrating expertise from neonatology, pediatrics, allergy, nutrition, and gastroenterology.
- Developed consensus-based recommendations reflecting both scientific data and clinical experience.
- Addressed the complexities of CMPA diagnosis across different pediatric stages.
Impact:
- Facilitates more accurate and timely diagnosis of CMPA in pediatric populations.
- Promotes enhanced, collaborative care among healthcare professionals involved in CMPA management.
- Aims to reduce the incidence of diagnostic errors and improve patient outcomes.
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