Retrospective Study Comparing Topography-Guided and Wavefront-Optimized LASIK Procedures in a Single Center

Area of Science:

• Ophthalmology
• Refractive Surgery
• Corneal Surgery

Background:

• Laser refractive surgery aims to correct vision errors.
• Customized treatment plans, including topography-guided and wavefront-optimized approaches, are used to enhance outcomes.
• Contoura with Phorcides (CP) and wavefront-optimized (WFO) are two such treatment modalities.

Purpose of the Study:

• To compare the visual outcomes of laser refractive surgery using the Contoura with Phorcides (CP) treatment plan versus the wavefront-optimized (WFO) treatment plan.
• To evaluate the efficacy of topography-guided (CP) versus wavefront-optimized (WFO) approaches in achieving superior visual acuity.

Main Methods:

• A retrospective chart review was conducted on 348 eyes undergoing laser refractive surgery with either CP or WFO treatment plans on the Wavelight EX500 platform.
• Data collected included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and refractive error.
• Postoperative visual acuity was compared to preoperative CDVA to assess visual gain.

Main Results:

• The CP group (227 eyes) showed a significantly higher percentage of eyes achieving 20/16 or better UDVA (57%) compared to the WFO group (17%) (p < 0.001).
• A greater proportion of eyes in the CP group gained one or more lines of UDVA compared to preoperative CDVA (47%) versus the WFO group (12%) (p < 0.001).
• Statistically significant differences were observed in refractive outcomes between the two groups.

Conclusions:

• Both topography-guided (CP) and wavefront-optimized (WFO) treatments yield excellent refractive results.
• The Contoura with Phorcides treatment plan demonstrated a superior ability to achieve 20/16 or better unaided distance vision compared to the wavefront-optimized treatment plan.