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Electroacupuncture versus exercise in patients with knee osteoarthritis: Study protocol for a randomized controlled
Xue-Zhou Wang1, Rui-Kang Wang2,3, Qiang Liu2,3
1International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.
Plos One
|June 11, 2024
Summary
This study compares electroacupuncture and exercise for knee osteoarthritis (KOA). Results will guide personalized KOA treatment by showing differences in effectiveness and cost-effectiveness between these popular physical therapies.
Area of Science:
- Orthopedics and Rehabilitation
- Pain Management
- Evidence-Based Medicine
Background:
- Knee osteoarthritis (KOA) is a prevalent condition in middle-aged and older adults.
- Electroacupuncture and exercise are common conservative treatments for KOA.
- Limited data exists comparing the direct clinical effects and cost-effectiveness of these two interventions.
Purpose of the Study:
- To evaluate and compare the clinical effectiveness of electroacupuncture versus exercise in managing symptomatic knee osteoarthritis.
- To assess the cost-effectiveness of electroacupuncture compared to exercise for KOA patients.
- To provide evidence to aid clinical decision-making in KOA management.
Main Methods:
- A randomized controlled trial involving 196 KOA patients, allocated 1:1 to electroacupuncture (n=98) or exercise (n=98) groups.
- Electroacupuncture group received treatment 3x/week for 8 weeks; exercise group received neuromuscular training 2x/week for 8 weeks.
- Co-primary outcomes: Numerical Rating Scale (NRS) and Knee injury and Osteoarthritis Outcome Score (KOOS) Activities of Daily Living (ADL) at 8 weeks.
Main Results:
- This section is to be filled once the study results are available.
Conclusions:
- The study is expected to elucidate differences between electroacupuncture and exercise for KOA.
- Findings will offer guidance for individualized treatment strategies in knee osteoarthritis management.
- Evidence generated will support informed clinical choices for KOA patients.

