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Updated: Jun 24, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
Published on: June 12, 2021
Hand in hand to successful immunotherapy: CD8+ T cells and M1-like macrophages swap the baton
Abir Hussein1, Slava Stamova1, Maria Xydia2
1Leibniz Institute for Immunotherapy, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.
Abstract:
Cancer immunotherapy is a pillar of clinical oncology but only achieves long-term remissions in a minority of cases. In this issue, van Elsas et al. show that effective immunotherapy requires a series of processes orchestrated by CD8+ T cells that result in the recruitment and local activation of M1-like macrophages.
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