Radioprotective Effect of Selenium Nanoparticles: A Mini Review
Rasool Azmoonfar1, Masoud Moslehi1, Daryoush Shahbazi-Gahrouei1
1Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Selenium nanoparticles show promise as radioprotective agents, offering antioxidant and anti-inflammatory benefits. These nanoparticles effectively protect organs from radiation damage without significant side effects, suggesting therapeutic potential.
Area of Science:
- Nanotechnology
- Radioprotection
- Biomedical Science
Background:
- Ionizing radiation poses risks in medical procedures.
- Developing effective radioprotective agents is crucial.
- Selenium nanoparticles (SeNPs) are being investigated for therapeutic applications.
Purpose of the Study:
- To systematically review the radioprotective effects of selenium nanoparticles.
- To evaluate the efficacy and safety of SeNPs against ionizing radiation damage.
- To explore potential therapeutic applications of SeNPs.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Comprehensive literature search across major scientific databases (PubMed, Scopus, Web of Science, Science Direct).
- Inclusion of 10 relevant studies after rigorous screening of 413 initial articles.
Main Results:
- Selenium nanoparticles exhibit significant anti-inflammatory and antioxidant properties.
- SeNPs demonstrated protective effects on kidneys, liver, and testicles against radiation-induced damage.
- Evidence supports efficient radioprotection with no significant adverse effects observed.
Conclusions:
- Selenium nanoparticles hold potential as effective radioprotective agents.
- SeNPs can mitigate the adverse effects of ionizing radiation exposure.
- Findings suggest therapeutic applications for SeNPs in medical imaging and radiotherapy contexts.
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