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Updated: Jun 24, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Practice-enhancing publications about the medication-use process in 2021.

Tyler A Vest^1,2, Nicholas P Gazda³, Daniel P O'Neil⁴

¹Duke University Health System, Durham, NC.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists

|June 12, 2024

Summary

This summary is machine-generated.

This review identifies and summarizes key 2021 literature impacting the medication-use process (MUP) in health-system pharmacy. It highlights practice-improving articles across prescribing, dispensing, administration, and monitoring for better medication safety.

Keywords:

administration computerized prescriber order entry dispensing medication use process monitoring prescribing

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Last Updated: Jun 24, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

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Published on: December 11, 2016

Novel Apparatus and Method for Drug Reinforcement

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Published on: February 19, 2021

Area of Science:

Pharmacy Practice
Health-System Pharmacy
Medication Safety

Background:

The medication-use process (MUP) is fundamental to safe medication utilization in healthcare.
The MUP encompasses prescribing/transcribing, dispensing, administration, and monitoring/medication reconciliation.
Continuous evaluation of MUP literature is crucial for practice improvement.

Purpose of the Study:

To identify, prioritize, and summarize 2021 literature impacting health-system pharmacy practice.
To assess the usefulness of evaluated MUP articles for practice improvement.
To provide health-system pharmacists with a curated list of impactful publications.

Main Methods:

Conducted a PubMed search in January 2022 for articles published in 2021.
Utilized targeted Medical Subject Headings (MeSH) keywords for literature search.
Searched tables of contents of selected pharmacy journals.
Reviewed 7,178 articles to identify 79 practice-enhancing publications.
Ranked articles by peer importance to select key publications from each MUP component.

Main Results:

Identified 79 practice-enhancing articles from 7,178 reviewed publications.
Categorized articles by MUP component: 15 (prescribing/transcribing), 17 (dispensing), 4 (administration), 21 (monitoring), 22 (monitoring/medication reconciliation).
Summarized highest-ranked articles and listed others for further review.

Conclusions:

Routinely reviewing literature and incorporating findings into daily practice is essential.
This article aids in identifying and summarizing impactful publications for health-system pharmacy.
Awareness of significant published studies empowers pharmacists to improve institutional MUP and practice.