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Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block: A Case Report
Michael Scott1, Natalie Jansen1, Leslie A Bilello1
1Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, Massachusetts.
Clinical Practice and Cases in Emergency Medicine
|June 13, 2024
Summary
A rare case of complete heart block occurred during ferric derisomaltose infusion, a new parenteral iron. This highlights the need to consider iron toxicity in cardiac events following infusions, especially with pre-existing conditions.
Area of Science:
- Cardiology
- Pharmacology
- Toxicology
Background:
- Ferric derisomaltose is a novel parenteral iron formulation known for its safety and tolerability.
- No acute, life-threatening cardiac events have been previously reported with ferric derisomaltose.
Purpose of the Study:
- To report a rare case of complete heart block associated with ferric derisomaltose administration.
- To suggest considering parenteral iron as a potential cause of cardiac events.
Main Methods:
- A case report of an 86-year-old male patient receiving ferric derisomaltose.
- Monitoring of patient's response during and after infusion.
- Cardiovascular assessment including ECG, pacing, and pacemaker implantation.
Main Results:
- The patient developed complete heart block six minutes into the infusion.
- Successful resuscitation and stabilization were achieved.
- A permanent pacemaker was implanted without complications.
Conclusions:
- Parenteral iron administration, including ferric derisomaltose, may be a potential cause of complete heart block.
- Consideration of iron toxicity is crucial in patients with cardiac conduction abnormalities presenting with heart block post-infusion.
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