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Neonatal Cardiac Rhabdomyoma: A Single-Center Experience
Başak Kaya1, Hasan Akduman1, Dilek Dilli1
1Neonatology, SBU Ankara Dr Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Zeitschrift Fur Geburtshilfe Und Neonatologie
|June 13, 2024
Summary
Neonatal cardiac rhabdomyomas, often linked to tuberous sclerosis complex, can spontaneously regress. Early diagnosis and management are key for favorable outcomes in affected newborns.
Area of Science:
- Pediatric Cardiology
- Neonatal Medicine
- Oncology
Background:
- Cardiac rhabdomyoma is the most frequent benign cardiac tumor in children.
- It is strongly associated with tuberous sclerosis complex (TSC).
- Neonatal diagnosis presents unique management challenges.
Purpose of the Study:
- To report a single-center experience with neonatal cardiac rhabdomyoma.
- To describe clinical observations, diagnostic methods, and treatments.
- To evaluate outcomes in neonates diagnosed with cardiac rhabdomyoma.
Main Methods:
- Retrospective clinical observational study.
- Inclusion of 12 newborn patients with cardiac rhabdomyoma.
- Review of data from the neonatal intensive care unit over 12 years.
Main Results:
- 50% of patients (6/12) had clinically identified tuberous sclerosis complex.
- Seven infants received everolimus; three were monitored.
- All surviving patients showed significant cardiac mass reduction and hospital discharge.
Conclusions:
- Cardiac rhabdomyomas frequently regress spontaneously in early childhood.
- Obstructive lesions or arrhythmias can lead to life-threatening complications.
- Prompt diagnosis, management, and monitoring are vital for neonates.
