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Updated: Jun 24, 2025

Dual-Color Fluorescence Cross-Correlation Spectroscopy to Study Protein-Protein Interaction and Protein Dynamics in Live Cells
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Novel Developments and Progress in Two-Dimensional Correlation Spectroscopy (2D-COS)

Yeonju Park1, Isao Noda2, Young Mee Jung1

  • 1Department of Chemistry, Institute for Molecular Science and Fusion Technology, and Kangwon Radiation Convergence Research Support Center, Kangwon National University, Chuncheon, Korea.

Applied Spectroscopy
|June 14, 2024
PubMed

Keywords:
2D-COSTwo-dimensional correlation spectroscopyreviewsurvey

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Homonuclear correlation spectroscopy (COSY) is a powerful technique used in Nuclear Magnetic Resonance (NMR) spectroscopy to study the correlations between nuclei of the same type within a molecule. It provides information about scalar couplings between adjacent nuclei, which helps determine connectivity and structural information. There are several COSY variants, each with its unique strengths and experimental parameters.
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