Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

2.0K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.0K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

780
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
780
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exercise-induced changes in hemostasis markers in marathon runners: effects of enzyme supplementation and determinants.

Frontiers in physiology·2026
Same author

Effects of exercise interventions on core health outcomes in patients with SLE: systematic review and meta-analysis.

Lupus science & medicine·2026
Same author

Sports Nutrition: Current and Novel Insights (2nd Edition).

Nutrients·2026
Same author

Goals in Nutrition Science 2025-2030.

Frontiers in nutrition·2026
Same author

Fragment-Based Online OzESI-MS, NMR, and Computational DP4+/DFT Approaches to the Characterization of the Putative Biosynthetic Lipid Precursor of Atkamine from Alaskan <i>Latrunculia</i> Sponges.

ACS omega·2026
Same author

Impact of preanalytical factors on plasma extracellular vesicles and human plasma proteome.

Clinical proteomics·2026

Related Experiment Video

Updated: Jun 24, 2025

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergstr&#246;m Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

40.2K

Beet supplementation mitigates post-exercise inflammation.

David C Nieman1, Camila A Sakaguchi1, James C Williams1

  • 1Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC, United States.

Frontiers in Nutrition
|June 14, 2024
PubMed
Summary
This summary is machine-generated.

A mixed beet-based supplement (BEET) increased nitrate and anti-inflammatory compounds post-exercise. BEET intake also reduced inflammation-related proteins, suggesting it moderates exercise-induced inflammation in athletes.

Keywords:
beetsexerciseinflammationoxylipinsproteomics

More Related Videos

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.6K
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

823

Related Experiment Videos

Last Updated: Jun 24, 2025

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergstr&#246;m Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

40.2K
Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.6K
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

823

Area of Science:

  • Exercise Physiology
  • Nutritional Biochemistry
  • Multi-omics

Background:

  • Intensive exercise, such as prolonged cycling, triggers inflammatory responses.
  • Nutritional interventions are explored to mitigate exercise-induced inflammation.
  • Beetroot-based supplements are rich in nitrates, which can be converted to nitric oxide, a known modulator of inflammation.

Purpose of the Study:

  • To investigate the efficacy of a mixed beet-based supplement (BEET) compared to a placebo (PL) in reducing inflammation following intensive cycling.
  • To analyze changes in oxylipins and protein expression using a multi-omics approach.

Main Methods:

  • A randomized, double-blind, placebo-controlled, crossover study was conducted with 20 cyclists.
  • Participants underwent two 2-week supplementation periods (BEET or PL) separated by a 2-week washout.
  • Blood samples were collected pre- and post-exercise to analyze oxylipins and proteomic profiles.

Main Results:

  • BEET supplementation significantly increased plasma nitrate and nitrite concentrations.
  • Two anti-inflammatory oxylipins (18-HEPE and 4-HDoHE) were elevated post-exercise with BEET.
  • Proteomic analysis revealed decreased levels of proteins involved in complement activation, acute phase response, and immune cell function with BEET.

Conclusions:

  • Two weeks of BEET supplementation increased plasma nitrate/nitrite and anti-inflammatory oxylipins.
  • BEET intake moderated protein biomarkers associated with exercise-induced inflammation.
  • These findings support the use of beetroot-based supplements to mitigate inflammation in athletes.