Interventional oncology in children: Where are we now?

Area of Science:

• Paediatric Oncology
• Interventional Radiology
• Cancer Research

Background:

• Paediatric interventional oncology (IO) development is hindered by a lack of specific outcome data.
• Reliance on adult IO experiences is suboptimal for unique paediatric tumour types like neuroblastoma and sarcomas.
• Paediatric interventional radiology frequently uses adapted or off-label techniques, impacting outcomes.

Purpose of the Study:

• To review current indications for interventional radiology in paediatric cancer care.
• To emphasize the role of locoregional approaches in paediatric oncology.
• To identify progress and future opportunities in paediatric IO.

Main Methods:

• Literature review of interventional oncology applications in paediatric cancer.
• Analysis of current indications from biopsy to supportive care.
• Exploration of disease-specific advancements and challenges.

Main Results:

• Interventional radiology (IR) plays a role in paediatric cancer diagnosis, treatment, and supportive care.
• Locoregional approaches are crucial for managing paediatric tumours.
• Progress has been made in specific paediatric oncological diseases, with identified areas for advancement.

Conclusions:

• There is a critical need for paediatric-specific data to advance interventional oncology.
• Tailored interventional techniques and research are essential for improving outcomes in childhood cancers.
• Further investigation into locoregional therapies holds promise for paediatric cancer treatment.