Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

6.8K
6.8K
DNA Isolation01:34

DNA Isolation

192.8K
DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.
192.8K
DNA Packaging00:58

DNA Packaging

102.4K
Overview
102.4K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

43.7K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.7K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

46.8K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
46.8K
DNA Agarose Gel Electrophoresis02:35

DNA Agarose Gel Electrophoresis

96.4K
Agarose gel electrophoresis is a laboratory technique commonly used to separate DNA fragments by size. However, it can also be used to isolate and purify DNA fragments using a gel extraction protocol.
Gel extraction follows five major steps: running gel electrophoresis to separate fragments, isolating the individual bands, extracting DNA from those bands, and removing the dye and salts from the extracted mixture to obtain pure DNA.
In cloning experiments, both the insert and vector DNA...
96.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review).

International journal of molecular medicine·2026
Same author

Comparison of VCV and PCV-VG modes on diaphragmatic function in diabetic patients undergoing laparoscopic colorectal surgery: a prospective randomized controlled study.

Annals of medicine·2026
Same author

Impact of different doses of remifentanil on postoperative pain and hyperalgesia: a prospective randomized controlled study and genotypic analysis.

Journal of clinical anesthesia·2026
Same author

Voltage-gated sodium channel 1.8 contributes to hyperalgesia induced by the coexistence of anxiety and remifentanil exposure.

The Korean journal of pain·2026
Same author

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Multiple Bone Cement Emboli in Heart and Inferior Vena Cava.

Journal of cardiothoracic and vascular anesthesia·2026

Related Experiment Video

Updated: Jun 23, 2025

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

12.4K

Storage-D: A user-friendly platform that enables practical and personalized DNA data storage.

Xiaoluo Huang1, Junting Cui1, Wei Qiang1

  • 1Shenzhen Key Laboratory of Synthetic Genomics Guangdong Provincial Key Laboratory of Synthetic Genomics, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen China.

Imeta
|June 17, 2024
PubMed
Summary

We developed Storage-D, a user-friendly platform for DNA data storage. It enables personalized data-to-DNA conversion and retrieval, enhancing data privacy and storage efficiency.

Keywords:
DNA data storageStorage‐Dcodec platform“Wukong” algorithm

More Related Videos

Author Spotlight: Harnessing DNA Barcode Technology to Enhance the Efficiency of Medicinal Plant Identification
08:55

Author Spotlight: Harnessing DNA Barcode Technology to Enhance the Efficiency of Medicinal Plant Identification

Published on: November 1, 2024

1.5K
A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.1K

Related Experiment Videos

Last Updated: Jun 23, 2025

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

12.4K
Author Spotlight: Harnessing DNA Barcode Technology to Enhance the Efficiency of Medicinal Plant Identification
08:55

Author Spotlight: Harnessing DNA Barcode Technology to Enhance the Efficiency of Medicinal Plant Identification

Published on: November 1, 2024

1.5K
A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.1K

Area of Science:

  • Biotechnology
  • Bioinformatics
  • Data Science

Background:

  • Deoxyribonucleic acid (DNA) is a promising medium for data storage.
  • Practical applications and user-oriented platforms for DNA data storage are lacking.

Purpose of the Study:

  • To develop a user-oriented platform for DNA data storage.
  • To enable personalized data conversion into DNA sequences and vice versa.

Main Methods:

  • Developed the Storage-D platform with a novel 'Wukong' algorithm.
  • Implemented user-selectable algorithms, error-correction, random-access, and codec pin strategies.
  • Integrated commercial DNA synthesis and sequencing platforms.

Main Results:

  • The 'Wukong' algorithm offers over 20 trillion codec pins for data privacy.
  • Achieved high coding potential (~1.98 bis/nt) with controlled GC content and homopolymer run length.
  • Successfully stored and retrieved COVID-19 treatment protocols in DNA sequences in vitro and in vivo.

Conclusions:

  • Storage-D provides a practical and personalized DNA data storage solution.
  • The platform demonstrates successful in vitro and in vivo DNA data storage.
  • Potential for wide-ranging applications in data archiving and security.