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Cavernous Sinus Thrombosis Secondary to Streptococcus Constellatus Pharynges
Natalia Jaramillo-Ángel1, Miguel Saro-Buendía1,2, Joan Carreres Polo3
1Departamento de Otorrinolaringología, Hospital Universitario y Politécnico La Fe, València, España.
Abstract:
Streptococcus constellatus pharyngis is a gram-positive commensal bacterium commonly found in the oropharynx, gastrointestinal and urogenital tracts. It might be an aggressive opportunistic pathogen causing invasive pyogenic infections in sterile areas, mostly as peritonsillar and orofacial abscesses. We report the case of a 6-year-old girl, who presented multiple head and neck abscesses and bilateral cavernous sinus thrombosis secondary to Streptococcus constellatus pharyngis. Cavernous sinus thrombosis, consequent to this microorganism, has not been reported to date in the literature. Due to the invasive features of this pathogen, a long-term antibiotherapy (up to 9 months) is required. Additionally, a surgical drainage is indicated in case of head and neck, or brain abscesses, larger than 20 or 25 mm respectively. Anticoagulation should be considered in case of venous thrombosis. The interest of this case is not only based on the rarity and severity of the disease, but also on the success of medical and surgical therapy (including long- term antibiotics, anticoagulation and two surgical procedures). This experience may serve as a guide to treat future cases.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s12070-024-04511-3.
Insights
A rare case of Streptococcus constellatus pharyngis caused multiple head and neck abscesses and cavernous sinus thrombosis in a child. Successful treatment involved long-term antibiotics, anticoagulation, and surgery.
Area of Science:
- Infectious Diseases
- Microbiology
- Otolaryngology
Background:
- Streptococcus constellatus pharyngis is a common commensal bacterium.
- It can act as an opportunistic pathogen, causing invasive pyogenic infections like abscesses.
- Invasive infections in sterile sites are rare but serious.
Purpose of the Study:
- To report a unique case of Streptococcus constellatus pharyngis causing head and neck abscesses and cavernous sinus thrombosis.
- To highlight the rarity and severity of this specific presentation.
- To provide insights into the successful management of such invasive infections.
Main Methods:
- Case report of a 6-year-old girl with multiple head and neck abscesses and bilateral cavernous sinus thrombosis.
- Diagnosis confirmed as Streptococcus constellatus pharyngis infection.
- Treatment involved a multidisciplinary approach including long-term antibiotics, anticoagulation, and surgical drainage.
Main Results:
- The patient presented with multiple head and neck abscesses and bilateral cavernous sinus thrombosis.
- Cavernous sinus thrombosis secondary to Streptococcus constellatus pharyngis is a novel finding in the literature.
- Successful outcomes were achieved with a combination of medical and surgical interventions.
Conclusions:
- Streptococcus constellatus pharyngis can cause severe, invasive infections beyond typical orofacial abscesses.
- Prompt and aggressive management, including long-term antibiotics, anticoagulation, and surgical intervention, is crucial for favorable outcomes.
- This case serves as a potential guide for managing similar rare and severe infections.
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