Related Experiment Video
Updated: Jun 23, 2025

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
Published on: February 16, 2020
Isolated Extra-Pulmonary Tuberculosis in ENT: A Commonly Missed Diagnosis
Bela J Prajapati1, Himanshu Bansal2, Meweu Ritse1
1Department of ENT, BJ Medical College and Civil Hospital, Ahmedabad, India.
Extrapulmonary tuberculosis (TB) in the head and neck region often mimics other conditions, leading to delayed diagnosis in adults. Early identification and high suspicion are crucial for effective management of this TB presentation.
Area of Science:
- Infectious Diseases
- Otolaryngology
- Oncology
Background:
- Tuberculosis (TB) represents a significant portion of general practice cases in India, particularly among HIV-negative adults.
- The head and neck region is a notable site for TB due to its diverse manifestations and potential for misdiagnosis as malignancy.
- Extrapulmonary TB (EPTB) in this region requires focused clinical attention due to its varied presentations.
Purpose of the Study:
- To highlight the diverse clinical presentations of isolated extrapulmonary TB in the head and neck region.
- To emphasize the importance of early diagnosis and high clinical suspicion for EPTB in head and neck cases.
- To discuss diagnostic modalities and management considerations for EPTB in the head and neck.
Main Methods:
- Prospective analysis of 60 patients diagnosed with TB over one year (July 2022 - June 2023).
- Patients presenting to the ENT Outpatient Department of Civil Hospital, Asarwa, with complete clinical data were included.
- Simple random sampling was employed for patient selection.
Main Results:
- The most commonly affected age group was the 3rd and 4th decades of life, with a male predominance.
- Cervical lymphadenitis was the most frequent presentation of EPTB in the head and neck, followed by tuberculous otitis media and laryngeal TB.
- Fine needle aspiration cytology (FNAC) was identified as an efficient diagnostic tool.
Conclusions:
- EPTB in the head and neck presents with characteristic clinical features, including cervical lymphadenitis, otitis media, and laryngeal TB.
- A high index of suspicion and prompt diagnosis are essential to prevent disease progression and complications.
- FNAC is a valuable diagnostic method for EPTB in the head and neck region.
Related Concept Videos
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pneumonia III: Complications and Assessment

