Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

225
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
225

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simultaneous Analysis of Microsaccades and Pupil Size Variations in Age-Related Cognitive Impairment Using Eye-Tracking Technology.

Journal of eye movement research·2026
Same author

Tactile-Sensation Imaging System for Assessing Material Inclusions in Breast Tumor Detection.

Biosensors·2026
Same author

SAR-Constrained Wireless Power Transfer Modeling for an Implantable Optical Neurostimulator Sensors.

Sensors (Basel, Switzerland)·2025
Same author

Design Optimization and Mechanical Performance Evaluation of a Modified Coronary IV-OCT Catheter Adapted for Intracranial Navigation: A Preclinical Study.

Biosensors·2025
Same author

Photobiomodulation at 660 nm Alleviates Alzheimer's Disease Pathology Through Amyloid-β Reduction and SIRT1 Upregulation in the Hippocampus of 5xFAD Mice.

International journal of molecular sciences·2025
Same author

Development of a Brain Catheter for Optical Coherence Tomography in Advanced Cerebrovascular Diagnostics.

Biosensors·2025

Related Experiment Video

Updated: Jun 23, 2025

A Protocol for Transcranial Photobiomodulation Therapy in Mice
13:07

A Protocol for Transcranial Photobiomodulation Therapy in Mice

Published on: November 18, 2018

12.2K

Photobiomodulation Therapy on Brain: Pioneering an Innovative Approach to Revolutionize Cognitive Dynamics.

Tahsin Nairuz1, Sangwoo-Cho1, Jong-Ha Lee1

  • 1Department of Biomedical Engineering, Keimyung University, Daegu 42601, Republic of Korea.

Cells
|June 19, 2024
PubMed
Summary

Photobiomodulation (PBM) therapy uses red to near-infrared light to treat brain disorders by enhancing cellular energy and reducing inflammation. Challenges in light delivery are being addressed by exploring new methods for effective brain treatment.

Keywords:
Parkinson’s diseasecognitive functionscytochrome c oxidaseintracranial and intranasal deliveryphotobiomodulation therapystroketranscranial approach

More Related Videos

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases
07:56

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases

Published on: June 28, 2024

697
Near Infrared NIr Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium
06:56

Near Infrared NIr Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium

Published on: March 14, 2015

9.9K

Related Experiment Videos

Last Updated: Jun 23, 2025

A Protocol for Transcranial Photobiomodulation Therapy in Mice
13:07

A Protocol for Transcranial Photobiomodulation Therapy in Mice

Published on: November 18, 2018

12.2K
Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases
07:56

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases

Published on: June 28, 2024

697
Near Infrared NIr Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium
06:56

Near Infrared NIr Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium

Published on: March 14, 2015

9.9K

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Photomedicine

Background:

  • Photobiomodulation (PBM) therapy utilizes red to near-infrared light for neurological and psychological disorders.
  • PBM's mechanism involves enhancing mitochondrial function (ATP synthesis) and cellular signaling pathways.
  • It promotes neuroprotection, neurogenesis, and synaptogenesis, offering potential therapeutic benefits.

Purpose of the Study:

  • To review the mechanisms of PBM therapy in the brain.
  • To summarize preclinical and clinical findings for various brain disorders.
  • To highlight PBM's potential as a novel therapeutic modality.

Main Methods:

  • Review of existing literature on PBM mechanisms and applications in brain disorders.
  • Analysis of preclinical investigations and clinical trials.
  • Discussion of transcranial, intracranial, and intranasal delivery methods.

Main Results:

  • PBM enhances neuronal metabolic capacity and triggers anti-oxidant, anti-inflammatory, and anti-apoptotic effects.
  • Evidence suggests PBM's efficacy in preclinical models and early clinical trials for dementia, stroke, Parkinson's disease, and depression.
  • Limited light penetration via transcranial methods necessitates alternative delivery strategies.

Conclusions:

  • PBM therapy demonstrates significant potential for treating a range of brain disorders and enhancing cognitive function.
  • Overcoming light delivery challenges is crucial for maximizing PBM's therapeutic impact.
  • PBM offers a promising alternative to conventional treatments, potentially impeding disease progression.