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Eccentric Muscle Strengthening Using Maximal Contractions Is Deleterious in Knee Osteoarthritis: A Randomized
Emmanuel Coudeyre1, Bruno Pereira2, Jean-Baptiste Lechauve1
1Service de Médecine Physique et de Réadaptation, CHU Clermont-Ferrand, Université Clermont Auvergne, INRAE, F-63000 Clermont-Ferrand, France.
Journal of Clinical Medicine
|June 19, 2024
Summary
Concentric strengthening showed greater improvements in quadriceps strength for knee osteoarthritis (OA) patients compared to eccentric training. Eccentric exercises also posed a higher risk of muscle injury, particularly to hamstrings.
Area of Science:
- Orthopedics
- Sports Medicine
- Rehabilitation
Background:
- Knee osteoarthritis (OA) is a degenerative joint disease characterized by pain and functional decline.
- Quadriceps strength is crucial for knee function and mobility in OA patients.
- Eccentric and concentric muscle strengthening are common rehabilitation strategies.
Purpose of the Study:
- To compare the efficacy of eccentric versus concentric isokinetic muscle strengthening in improving quadriceps strength in individuals with knee OA.
- To assess the safety and adverse event profiles of both training modalities.
Main Methods:
- A randomized controlled study involving 12 sessions of isokinetic strengthening over 6 weeks.
- Participants aged 40-70 with predominantly unilateral femorotibial OA were recruited.
- Primary outcome: change in concentric isokinetic knee extension peak torque; Secondary outcomes: hamstring strength, walking speed, pain, and functional status (WOMAC).
Main Results:
- Concentric strengthening led to greater improvements in quadriceps strength compared to eccentric training, though not statistically significant.
- The eccentric training group experienced a 25% rate of major adverse events.
- No significant differences were observed in secondary outcomes between groups at 6 weeks or 6 months.
Conclusions:
- Concentric training appears more effective than eccentric training for enhancing quadriceps strength in knee OA.
- Eccentric training is associated with a higher risk of muscle injury, especially hamstring injuries.
- Further research is needed to optimize eccentric training protocols for OA rehabilitation.

