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The Association Between Sleep Problems and Attentional Network Functions in Patients with Self-Limited Epilepsy with
Nan Jiang1,2, Chun Mei Yang1,2, Jia Le Wang1,2
1Children's Medical Centre of Anhui Medical University, Hefei, Anhui, People's Republic of China.
Insights
Children with self-limited epilepsy with central temporal spiking (SeLECTS) experience more sleep problems and attention deficits. Addressing sleep issues in SeLECTS children may improve their quality of life.
Area of Science:
- Pediatric Neurology
- Sleep Medicine
- Neurodevelopmental Disorders
Background:
- Self-limited epilepsy with central temporal spiking (SeLECTS) is a common childhood epilepsy syndrome.
- Sleep disturbances are frequently reported in children with epilepsy, but specific data for SeLECTS are limited.
- Attention network dysfunction is a potential comorbidity in neurological disorders.
Purpose of the Study:
- To investigate sleep problems in children diagnosed with SeLECTS.
- To evaluate the relationship between sleep disturbances and attention network dysfunction in this population.
- To identify specific sleep issues prevalent in children with SeLECTS.
Main Methods:
- A cohort of 107 children (6-14 years) with SeLECTS and 90 healthy controls were assessed.
- Sleep status was evaluated using the Children's Sleep Habits Questionnaire (CSHQ).
- Attentional network function was measured using the Attention Network Test (ANT).
Main Results:
- Children with SeLECTS showed significantly higher CSHQ scores and sleep disorder incidence compared to controls (P<0.001).
- Specific sleep issues included delayed sleep onset, shorter sleep duration, night awakenings, parasomnias, daytime sleepiness, and sleep anxiety (P<0.01).
- Total CSHQ scores correlated negatively with ANT correct rates and alerting/executive control network efficiency, and positively with reaction time.
Conclusions:
- Children with SeLECTS have a higher prevalence of sleep disorders than healthy peers.
- The severity of attention network dysfunction is positively correlated with the severity of sleep disorders in SeLECTS.
- Interventions targeting sleep problems may enhance the prognosis and quality of life for children with SeLECTS.
Purpose:
To investigate sleep problems in children with self-limited epilepsy with central temporal spiking (SeLECTS) and to assess the relationship between sleep problems and attention network dysfunction.
Patients And Methods:
107 children 6-14 years of age with SeLECTS and 90 age- and sex-matched healthy controls were recruited for this study. The sleep status of these participants was evaluated using the Children's Sleep Habits Questionnaire (CSHQ), while attentional network function was assessed with the attention network function test (ANT).
Results:
Together, these analyses revealed that children with SeLECTS exhibited higher total CSHQ scores and sleep disorder incidence relative to healthy controls (P< 0.001). Children with SeLECTS had higher scores in delayed sleep onset, sleep duration, night awakenings, parasomnias, daytime sleepiness and sleep anxiety (P<0.01). Total CSHQ scores were negatively correlated with average ANT correct rates (ρ= -0.253, P<0.01), while they were positively correlated with total reaction time (ρ=0.367, P<0.01) and negatively correlated with the efficiency of the alerting and executive control networks (ρ=-0.344 P<0.01; ρ=-0.418 P<0.01).
Conclusion:
Children with SeLECTS face a higher risk of experiencing sleep disorders relative to age-matched healthy children, while also demonstrating that the magnitude of the impairment of attentional network function in these children is positively correlated with sleep disorder severity. Thus, the prognosis and quality of life of children with SeLECTS can be improved by interventions addressing sleep disorders.
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