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Updated: Jun 23, 2025

Murine Fecal Isolation and Microbiota Transplantation
Published on: May 26, 2023
Cardiovascular disease therapeutics via engineered oral microbiota: Applications and perspective
Wenyu Zhen1, Zifei Wang1, Qing Wang1
1Key Laboratory of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology Anhui Medical University Hefei China.
Abstract:
Engineering bacteria are considered as a potential treatment for cardiovascular diseases and related risk factors. Oral bacteria are closely related to the occurrence and development of cardiovascular diseases, and their engineering has broad prospects and potential in the treatment of cardiovascular diseases. Oral pathogenic bacteria undergo protein and genetic engineering, including the incorporation of exogenous plasmids to yield therapeutic effects; genetically engineered oral probiotics can be harnessed to secrete cytokines and reactive oxygen species, offering novel therapeutic avenues for cardiovascular diseases.
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