Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

44.4K
Overview
44.4K
Development of Immunocompetence01:22

Development of Immunocompetence

301
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
301
Immunological Memory01:23

Immunological Memory

590
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
590
Current Trends in Nursing II01:30

Current Trends in Nursing II

1.2K
Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
1.2K
Active versus Passive Immunity01:31

Active versus Passive Immunity

622
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
622
Cancer Vaccines01:30

Cancer Vaccines

352
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
352

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Placental Pathogens Associated With Adverse Maternal and Neonatal Outcomes.

Open forum infectious diseases·2026
Same author

Maternal Respiratory Syncytial Virus Prefusion F Vaccination and Acute Respiratory Illness in Infants.

JAMA network open·2026
Same author

Comparison of influenza hemagglutination inhibition titers from capillary blood versus venipuncture.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same author

Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial.

Pediatrics·2026
Same author

Glycemia Range and Offspring Weight and adiposity in response To Human milk (GROWTH) study: protocol for an observational cohort designed to study lactational programming.

BMJ open·2026
Same author

The Impact of Maternal Influenza Infection and Vaccination During Pregnancy on Birth Outcomes.

The Pediatric infectious disease journal·2026

Related Experiment Video

Updated: Jun 23, 2025

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
13:00

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

3.6K

Maternal Immunizations: Past, Present, and Future.

Anne-Marie Rick1, Richard Beigi2,3

  • 1Department of Pediatrics, Division of General Academic Pediatrics, University of Pittsburgh School of Medicine.

Clinical Obstetrics and Gynecology
|June 20, 2024
PubMed
Summary

Maternal vaccines like those for influenza and pertussis protect pregnant individuals and newborns. These immunizations transfer antibodies, providing crucial early-life immunity and preventing severe illness.

More Related Videos

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring
09:09

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring

Published on: August 17, 2022

1.6K
Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
07:51

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface

Published on: May 21, 2015

17.2K

Related Experiment Videos

Last Updated: Jun 23, 2025

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
13:00

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

3.6K
Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring
09:09

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring

Published on: August 17, 2022

1.6K
Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
07:51

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface

Published on: May 21, 2015

17.2K

Area of Science:

  • Immunology
  • Maternal and Child Health
  • Vaccinology

Background:

  • Pregnancy involves significant physiological changes that can increase susceptibility to infections.
  • Newborns are vulnerable to severe complications from various infectious diseases in early life.
  • Maternal vaccination is a key strategy to protect both pregnant individuals and infants.

Purpose of the Study:

  • To summarize the importance and recommendations for maternal vaccines during pregnancy.
  • To highlight the immunological mechanisms by which maternal vaccines protect infants.
  • To underscore the established safety and efficacy of recommended maternal immunizations.

Main Methods:

  • Review of current recommendations from health authorities like the CDC.
  • Synthesis of research data on the safety and efficacy of key maternal vaccines.
  • Explanation of antibody transfer from mother to fetus/neonate.

Main Results:

  • Routine vaccination against influenza, pertussis, COVID-19, and RSV is recommended during pregnancy.
  • Maternal vaccination leads to transplacental antibody transfer, conferring passive immunity to the infant.
  • Studies confirm the safety and effectiveness of these vaccines in pregnant populations.

Conclusions:

  • Maternal vaccines are a critical public health intervention for protecting pregnant individuals and newborns.
  • Vaccination during pregnancy enhances infant immunity during a vulnerable period.
  • Continued research and adherence to vaccination schedules are vital for maternal and child health.