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Related Experiment Video

Updated: Jun 23, 2025

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Associations Between Stroke Type, Ischemic Stroke Subtypes, and Post-Stroke Cognitive Trajectories.

Deborah A Levine^1,2, Rachael T Whitney¹, Wen Ye³

¹Department of Internal Medicine, University of Michigan (U-M), Ann Arbor, MI.

Medrxiv : the Preprint Server for Health Sciences

|June 21, 2024

Summary

Post-stroke cognitive decline occurs in multiple domains for both ischemic and hemorrhagic stroke survivors. These cognitive declines did not significantly differ based on stroke type or specific ischemic stroke subtypes.

Keywords:

Blood Pressure Cerebrovascular Disease/Stroke Cholesterol Cognition Cognitive Impairment Glucose Health Services Quality and Outcomes Risk Factors Stroke

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Last Updated: Jun 23, 2025

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

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Author Spotlight: Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

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Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Area of Science:

Neurology
Cognitive Science
Epidemiology

Background:

Understanding post-stroke cognitive trajectories is crucial.
Differences in cognitive decline by stroke type and subtype remain unclear.

Purpose of the Study:

To investigate associations between stroke types (ischemic, hemorrhagic) and ischemic stroke subtypes with post-stroke cognitive decline.
To analyze changes in global cognition, executive function, and memory after stroke.

Main Methods:

Pooled cohort analysis of 1,143 dementia-free individuals with acute stroke.
Utilized linear mixed-effects models to estimate cognitive changes over a median follow-up of 6 years.
Standardized cognitive outcomes as T-scores for comparison.

Main Results:

Initial post-stroke cognitive scores did not differ between ischemic and hemorrhagic stroke survivors.
Ischemic stroke survivors showed declines in global cognition, executive function, and memory.
Cognitive declines did not differ between stroke types or among ischemic stroke subtypes, including small vessel disease.

Conclusions:

Stroke survivors experience cognitive decline across multiple domains.
Cognitive decline trajectories are similar regardless of stroke type or ischemic stroke subtype.