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Linear Leucoderma Following Intralesional Steroid Injection.

Anjana Beena¹, Ranjeeta Sapam², Gurumayum Chitralekha Devi²

¹Dermatology, Jawaharlal Nehru Institute of Medical Sciences, Imphal, IND.

|June 21, 2024

Summary

Intralesional steroid injections can cause local side effects, including rare linear leukoderma. This case highlights a patient developing depigmentation after triamcinolone acetonide injection for a ganglion cyst.

Keywords:

depimented macules hypopigmented macules intralesional steroid injection leucoderma linear leucoderma

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Area of Science:

Dermatology
Endocrinology

Background:

Intralesional steroid injections offer an alternative to systemic administration, potentially avoiding systemic side effects like hypothalamus-pituitary-adrenal axis suppression.
However, local side effects such as pain, atrophy, and pigmentary changes can still occur following intralesional steroid therapy.

Observation:

A 23-year-old female presented with linear depigmentation on her left forearm.
The depigmentation appeared three months after a single intralesional injection of triamcinolone acetonide to treat a ganglion cyst.

Findings:

The case demonstrates linear leukoderma, a rare but recognized complication of intralesional steroid injections.
This specific instance involved triamcinolone acetonide, commonly used for ganglion cysts.

Implications:

Clinicians should be aware of the potential for iatrogenic pigmentary changes, such as linear leukoderma, following intralesional steroid injections.
This case underscores the importance of patient counseling regarding the full spectrum of potential side effects, including rare dermatological complications.