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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Related Experiment Video

Updated: Jan 17, 2026

Kinetic Analysis of Vasculogenesis Quantifies Dynamics of Vasculogenesis and Angiogenesis In Vitro
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Koebnerization in Vasculitis: An Unusual Clinical Observation.

Demita Nambam1, Ranjeeta Sapam1, Gurumayum Chitralekha Devi1

  • 1Dermatology, Venereology, and Leprosy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, IND.

Cureus
|September 22, 2025
PubMed
Summary

Koebner's phenomenon, the development of skin lesions after trauma, is rarely seen in cutaneous vasculitis. This case highlights trauma as a potential trigger for vasculitic dermatoses, suggesting inflammation or immune responses.

Area of Science:

  • Dermatology
  • Immunology
  • Pathology

Background:

  • Koebner's phenomenon (KP) describes isomorphic skin lesions appearing after trauma in dermatoses.
Keywords:
drug induced vasculitisisomorphic responsekoebner’s phenomenonleukocytoclastic vasculitissmall vessel vasculitistrauma-induced lesions

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  • KP is common in psoriasis, lichen planus, and vitiligo.
  • Its occurrence in cutaneous vasculitis is exceptionally rare.