Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

231
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
231
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

115
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
115
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

11.6K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of primary total hip arthroplasty in patients who have a BMI less than 20.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026
Same author

Cementless Total Knee Arthroplasty Is Associated With Improved Outcomes in Patients Who Have a Body Mass Index of 35 or More.

The Journal of arthroplasty·2026
Same author

Risk Factors for Tibial Periprosthetic Fractures After Total Knee Arthroplasty: The Influence of Fixation and Implant Design.

The journal of knee surgery·2026
Same author

Epidemiology and Classification of Tibial Periprosthetic Fractures Following Total Knee Arthroplasty.

The journal of knee surgery·2026
Same author

Intraoperative Tibial Periprosthetic Fractures During Total Knee Arthroplasty: Incidence, Risk Factors, and Early Outcomes.

The journal of knee surgery·2026
Same author

Management Strategies for Tibial Periprosthetic Fractures After Total Knee Arthroplasty.

The journal of knee surgery·2026
Same journal

Lateral Femoral Condyle Angle Is an Anatomic Risk Factor for Anterior Cruciate Ligament Primary Injury and Secondary Graft Rerupture.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same journal

Labral Hypoplasia by Preoperative Magnetic Resonance Imaging Predicts Higher Revision and Arthroplasty Risk After Hip Arthroscopy for Femoroacetabular Impingement Syndrome at 10 Year Follow-Up.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same journal

Hip Arthroscopic Labral Repair for Femoroacetabular Impingement Yields High Return-to-Sport Rates and Improved Outcomes in Basketball Players.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same journal

Editorial Commentary: Adding a Modified Lemaire Reconstruction to Anterior Cruciate Ligament Reconstruction Does Not Affect the Forgotten Joint Score-12 at 2 Years.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same journal

Modified Lemaire Anterolateral Corner Reconstruction Does Not Impact Forgotten Joint Score-12 at 2 Years in Hamstring Graft Anterior Cruciate Ligament Reconstructions in High-Risk Patients.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same journal

Adding a Lateral Extra-articular Tenodesis to Quadriceps Autograft Anterior Cruciate Ligament Reconstruction Reduces Risk of Graft Failure.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
See all related articles

Related Experiment Video

Updated: Jun 23, 2025

Knee Arthrocentesis in Adults
04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

7.4K

Corticosteroid Injections Within 2 Weeks After Knee Arthroscopy Are Associated With Increased Infection Risk.

Jeremy Dubin1, Hytham Salem1, Oliver Sax1

  • 1Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, Maryland, U.S.A.

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association
|June 21, 2024
PubMed
Summary
This summary is machine-generated.

Corticosteroid injections (CSIs) within two weeks after knee arthroscopy significantly increase the risk of postoperative infection. Injections within four weeks also raise infection risk, but to a lesser extent.

More Related Videos

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

1.4K
Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
04:57

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

518

Related Experiment Videos

Last Updated: Jun 23, 2025

Knee Arthrocentesis in Adults
04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

7.4K
Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

1.4K
Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
04:57

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

518

Area of Science:

  • Orthopedic surgery
  • Infectious disease epidemiology
  • Pharmacology

Background:

  • Postoperative infections following arthroscopy can lead to significant morbidity.
  • Corticosteroid injections (CSIs) are sometimes used postoperatively for pain and inflammation management.
  • The optimal timing for administering CSIs after arthroscopy to minimize infection risk is not well-established.

Purpose of the Study:

  • To evaluate the association between the timing of postoperative corticosteroid injections (CSIs) and the risk of 90-day infection after knee arthroscopy.
  • To stratify infection risk based on specific postoperative CSI administration intervals: 0-2 weeks, 2-4 weeks, 4-6 weeks, and 6-8 weeks.

Main Methods:

  • Retrospective analysis of a large, all-payer national database.
  • Inclusion of patients undergoing knee arthroscopy.
  • Definition of postoperative infection based on International Classification of Diseases (ICD-9/10) and Current Procedural Terminology (CPT) codes for septic knee or surgical-site infection.
  • Multivariable regression analysis to determine the odds ratio (OR) of infection at 90 days.

Main Results:

  • Corticosteroid injections (CSIs) administered within 0-2 weeks post-arthroscopy were associated with a significantly increased odds of 90-day infection (OR, 3.31; P < .001).
  • CSIs given between 2-4 weeks post-arthroscopy also showed a higher risk of infection (OR, 2.72; P = .003).
  • Comparing the two earliest intervals, CSIs within 0-2 weeks had a greater odds of infection (OR, 2.50) than those within 2-4 weeks.

Conclusions:

  • Corticosteroid injections administered within the first two weeks after knee arthroscopy pose the highest risk for postoperative infection.
  • While CSIs within four weeks increase infection risk, the magnitude of risk is greatest with earlier administration.
  • These findings suggest a need for careful consideration of the timing of CSIs post-arthroscopy to mitigate infection risk.