Related Experiment Video
Updated: May 2, 2026
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
15.9K
Blue Toe Syndrome in Behçet's Disease: A Case Report
Qusai Aljarrah1, Saleh A Ba-Shammakh2, Mohammed Z Allouh2,3
1Department of General and Vascular Surgery, King Abdullah University Hospital (KAUH), Jordan University of Science and Technology (JUST), Irbid, Jordan.
The American Journal of Case Reports
|June 22, 2024
Summary
Vascular Behçet's disease can cause blue toe syndrome due to small-vessel vasculitis. This rare presentation requires careful evaluation to distinguish it from other conditions like Raynaud's phenomenon.
Area of Science:
- Vascular Medicine
- Rheumatology
- Immunology
Background:
- Vascular Behçet's disease (VBD) is a rare multisystemic vasculitis affecting arteries and veins.
- It predominantly impacts males from Silk Road regions, with arterial complications being severe and lethal.
- While large-vessel involvement is common, data on isolated small-vessel arterial disease in VBD is limited.
Observation:
- A 51-year-old man presented with unilateral blue toe syndrome.
- This rapidly progressed to dry gangrene of the toes.
- This case highlights an atypical presentation of VBD involving small-vessel vasculitis.
Findings:
- Isolated small-vessel vasculitis can manifest as blue toe syndrome in VBD.
- Digital ischemia due to microvascular occlusion is a rare but significant complication.
- Distinguishing this from vasospastic conditions like Raynaud's phenomenon is crucial.
Implications:
- This case emphasizes the need for thorough evaluation of small-vessel vasculitis in VBD patients.
- Accurate diagnosis is essential for appropriate management and differentiating from conditions with different prognoses.
- Clinical vigilance is required to identify inflammatory microvascular occlusive disease versus vasospastic syndromes.
Related Concept Videos
01:17Chronic Bowel Disorders: Introduction
900
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
900
01:25Endocarditis II: Clinical Features of Infective Endocarditis
929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929