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Get2PrEP2-A Provider Messaging Strategy to Improve PrEP Uptake: A Randomized Controlled Quality Improvement Project.

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Provider messaging about HIV preexposure prophylaxis (PrEP) for patients with STIs modestly increased documented discussions. This intervention shows potential for improving PrEP access and HIV prevention efforts.

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Area of Science:

  • Public Health
  • Infectious Disease Prevention
  • Health Informatics

Background:

  • HIV preexposure prophylaxis (PrEP) is crucial for preventing HIV transmission.
  • Diagnoses of bacterial sexually transmitted infections (STIs) indicate a potential need for HIV PrEP.
  • Previous studies showed electronic medical record (EMR) laboratory comments did not enhance PrEP discussions.

Purpose of the Study:

  • To evaluate if personalized provider messaging via EMR increases documentation of HIV PrEP discussions, referrals, or provision.
  • To assess the impact of active, personalized messaging on HIV PrEP uptake indicators in patients diagnosed with STIs.

Main Methods:

  • A parallel 3-arm, unblinded, randomized controlled trial (Get2PrEP2) was conducted.
  • Participants were allocated 2:1 to intervention or standard care.
  • Intervention involved provider messaging through EMR chat or email.

Main Results:

  • A modest 7.8% increase in documented PrEP discussions was observed in the intervention group compared to standard care.
  • No significant difference was found between EMR chat and email messaging modalities.
  • Documented discussions were more frequent in outpatient/emergency departments, among women, and individuals under 25.

Conclusions:

  • Targeted provider messaging for STI patients has a small but significant effect on documenting PrEP discussions.
  • Further research is needed to confirm if this messaging increases actual PrEP uptake and improves long-term outcomes.