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Transitional cell carcinoma of the prostate
European Urology
|January 1, 1985
Summary
Transitional cell carcinoma of the prostate is rare, accounting for 1.5% of cases. This urothelial neoplasia presents similarly to adenocarcinoma but has a poor prognosis.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Transitional cell carcinoma (TCC) of the prostate is a rare malignancy.
- It represents 1.5% of all prostate carcinomas.
- Distinguishing primary prostatic TCC from secondary involvement is crucial.
Purpose of the Study:
- To present five cases of primary transitional cell carcinoma of the prostate.
- To analyze clinical presentation, associations, and survival outcomes.
- To reinforce the classification of prostatic TCC as an urothelial neoplasm.
Main Methods:
- Retrospective review of 323 consecutive prostatic carcinoma cases.
- Inclusion criteria: primary TCC, excluding tumors contiguous to bladder carcinoma or expressing prostatic acid phosphatase.
- Analysis of patient demographics, clinical data, and survival.
Main Results:
- Five cases (1.5%) of primary prostatic TCC were identified.
- Mean age at diagnosis was 70 years.
- Associated with adenocarcinoma in 20% and non-contiguous bladder carcinoma in 40%.
- Mean survival was 10.6 months, with 60% mortality within 6 months.
Conclusions:
- Prostatic TCC is a distinct entity with poor prognosis.
- It shares clinical similarities with prostatic adenocarcinoma.
- Findings support the classification of prostatic TCC as an urothelial neoplasm.