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[Translated article] Therapeutic management, adherence, and clinical outcomes of heart failure in Andalucía. ANDALIC
Héctor Rodríguez-Ramallo1, Nerea Báez-Gutiérrez2, Didiana Jaramillo-Ruiz1
1Unidad de gestión clínica de farmacia, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Insights
This study examines heart failure patient data in Andalusia, focusing on treatment, adherence, and outcomes. Findings aim to improve patient care and reduce the regional health burden of heart failure.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Heart failure (HF) is a widespread condition with high mortality and significant healthcare costs.
- Limited systematic data on HF patient treatment and adherence hinders outcome improvement.
Purpose of the Study:
- To characterize clinical features, therapeutic strategies, adherence, and outcomes in Andalusian HF patients.
- To investigate associations between patient characteristics, management, adherence, and clinical results.
Main Methods:
- Observational, population-based, retrospective cohort study.
- Data extracted from the Andalusian population health database (2014-2023).
- Statistical analysis includes descriptive, bivariate, and multivariate (logistic, Cox, Poisson) regression models.
Main Results:
- Descriptive analysis of patient cohort characteristics, adherence, and clinical outcomes.
- Bivariate and multivariate analyses to identify factors associated with adherence, persistence, and outcomes.
- Evaluation of temporal changes in outcomes using Poisson regression.
Conclusions:
- The study will provide insights into HF management and adherence in Andalusia.
- Findings are expected to inform optimized strategies for improving patient care and quality of life.
- Results could help mitigate the regional health burden of heart failure.
Abstract:
Heart failure is a prevalent syndrome with high mortality rates, representing a significant economic burden in terms of healthcare. The lack of systematic information about the treatment and adherence of patients with heart failure limits the understanding of these aspects and potentially the improvement of clinical outcomes.
Objective:
To describe the clinical characteristics, therapeutic management, adherence, persistence, and clinical results, as well as the association between these variables, in a cohort of patients with heart failure in Andalusia.
Design:
This study will be an observational, population-based, retrospective cohort study. Data of patients discharged from an Andalusian hospital with a diagnosis of heart failure between 2014 and 2023 will be extracted from the Andalusian population health database.
Analysis:
The statistical analysis will incorporate the following strategies: (1) Descriptive analysis of the characteristics of the population cohort, adherence measures, and clinical outcomes. (2) Bivariate analyses to study the association of covariates with adherence, persistence, and clinical results. (3) Multivariate logistic regression and Cox regression analysis including relevant covariates. (4) To evaluate changes over time, multivariate Poisson regression models will be used. By conducting this comprehensive study, we aim to gain valuable insights into the clinical characteristics, treatment management, and adherence of heart failure patients in Andalusia, as well as to identify factors that may influence clinical outcomes. These findings could be critical both for the development of optimised strategies that improve medical care and quality of life of patients and for mitigating the health burden of HF in the region.
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