Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
Bone Disorders01:29

Bone Disorders

3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

3.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
3.9K
Bone Remodeling01:40

Bone Remodeling

38.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.3K
Bone Structure01:55

Bone Structure

48.1K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
48.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis and Biological Evaluations of New 4,5-Diphenyl-Imidazole-Indole-N-Phenylacetamide Derivatives Against α-glucosidase and Acetylcholinesterase.

Archiv der Pharmazie·2026
Same author

National and subnational burden and attributable risk factors of osteoarthritis, rheumatoid arthritis, and low back pain in Iran: 1990-2019 findings of the Global Burden of Disease (GBD) Study.

PloS one·2026
Same author

Enhancing Medical Education: The Role of Artificial Intelligence Tools in the Teaching-Learning Process.

Advances in medical education and practice·2026
Same author

Histopathological Effects of the Intrathecal Chondroitinase ABC Administration in Spinal Cord Injured Rats: A Systematic Review.

Basic and clinical neuroscience·2026
Same author

National program for cardiovascular disease and hypertension in primary healthcare: WHO-PEN program initial scale-up in Iran (IraPEN).

BMC cardiovascular disorders·2026
Same author

Association Between Dietary/Supplementary Calcium Intake and Risk of Breast Cancer: A Systematic Review and Meta-Analysis of Cohort Studies.

Nutrition and cancer·2026

Related Experiment Video

Updated: Jun 22, 2025

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.2K

Osteoporosis e-learning courses: A systematic review to develop a comprehensive virtual course for General

Roya Naemi1, Mahnaz Sanjari2, Maryam Aalaa3

  • 1Department of Health Information Management, School of Paramedical Sciences, Ardabil University of Medical Sciences, Ardabil, Iran.

Journal of Diabetes and Metabolic Disorders
|June 27, 2024
PubMed
Summary

This study developed an online osteoporosis management course for general practitioners (GPs) by reviewing existing e-learning resources. The aim is to enhance early diagnosis and treatment of osteoporosis.

Keywords:
E-learningHealthcare providersOsteoporosis

More Related Videos

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

438
Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

490

Related Experiment Videos

Last Updated: Jun 22, 2025

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.2K
Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

438
Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

490

Area of Science:

  • Medical Education
  • Osteoporosis Management
  • Digital Health

Background:

  • Effective osteoporosis management requires healthcare professional training in early diagnosis and treatment.
  • Existing e-learning courses were reviewed to inform the development of a new online program.

Purpose of the Study:

  • To investigate global e-learning courses on osteoporosis.
  • To develop a comprehensive online osteoporosis management course tailored for general practitioners (GPs).

Main Methods:

  • Systematic review of databases (Web of Science, Scopus, PubMed, Embase, ERIC) and Google searches.
  • Independent content extraction and verification by two researchers.
  • Development and expert panel approval of online course modules for GPs.

Main Results:

  • 22 e-learning courses from 3 studies and 19 websites were analyzed.
  • Osteoporosis e-learning content was categorized into ten themes.
  • Final online course modules cover bone measurement, diagnosis, clinical management, monitoring, and sarcopenia.

Conclusions:

  • A systematic approach yielded e-learning modules for osteoporosis management.
  • The developed course aims to improve GPs' knowledge and skills in osteoporosis care.
  • This online resource can enhance practical management of osteoporosis.