Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

From DNA to Protein03:06

From DNA to Protein

18.3K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
18.3K
The Central Dogma01:25

The Central Dogma

125.1K
Overview
125.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Programmable DNA Hydrogels as Artificial Extracellular Matrix.

Small (Weinheim an der Bergstrasse, Germany)·2022
Same author

Ionic Current Fluctuation and Orientation of Tetrahedral DNA Nanostructures in a Solid-State Nanopore.

Small (Weinheim an der Bergstrasse, Germany)·2022
Same author

Benzyl-rich ligand engineering of the photostability of atomically precise gold nanoclusters.

Chemical communications (Cambridge, England)·2022
Same author

Catalytic Nucleic Acids for Bioanalysis.

ACS applied bio materials·2022
Same author

Impact of Graphene Exposure on Microbial Activity and Community Ecosystem in Saliva.

ACS applied bio materials·2022
Same author

Driving DNA Origami Assembly with a Terahertz Wave.

Nano letters·2021
Same journal

The heterogeneous treatment effects and joint effects of high-speed rail construction and low-carbon city pilot policy on urban economic resilience.

Fundamental research·2026
Same journal

Multiple waves of westward dry-land agriculture expansions along the East Silk Road during the Neolithic age.

Fundamental research·2026
Same journal

Biomedical imaging.

Fundamental research·2026
Same journal

Artificial intelligence in echocardiography: Applications and future directions.

Fundamental research·2026
Same journal

Performance of lunar shell structure for moonbase subjected to low gravity coupled with changing temperature.

Fundamental research·2026
Same journal

KREEP materials recorded in impact glasses of Chang'e-6 regolith returned from the South Pole-Aitken Basin.

Fundamental research·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2025

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
11:02

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Published on: September 14, 2018

7.8K

Highly reliable and efficient encoding systems for hexadecimal polypeptide-based data storage.

Yubin Ren1, Yi Zhang2, Yawei Liu2

  • 1Department of Chemistry, Tsinghua University, Beijing 100084, China.

Fundamental Research
|June 27, 2024
PubMed
Summary
This summary is machine-generated.

New encoding systems, RaptorQ-Arithmetic-Base64-Shuffle-RS (RABSR) and RaptorQ-Arithmetic-Huffman-Rotary-Shuffle-RS (RAHRSR), enable efficient and reliable polypeptide-based data storage. These systems significantly improve data density and error correction for digital information.

Keywords:
BiomaterialData storageEncoding systemHexadecimalPolypeptide

More Related Videos

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
14:02

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

8.5K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K

Related Experiment Videos

Last Updated: Jun 22, 2025

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
11:02

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Published on: September 14, 2018

7.8K
Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
14:02

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

8.5K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K

Area of Science:

  • Biotechnology
  • Information Science
  • Materials Science

Background:

  • Polypeptide sequences offer high-density information storage potential.
  • Existing encoding systems are inadequate for polypeptide synthesis, storage, and sequencing challenges.
  • This gap limits the use of polypeptides for large-scale digital data archiving.

Purpose of the Study:

  • To develop novel encoding systems for efficient and reliable polypeptide-based data storage.
  • To address limitations in data compression, error correction, and sequence integrity.
  • To enable the practical application of polypeptides for digital information archiving.

Main Methods:

  • Development of two novel encoding systems: RABSR and RAHRSR.
  • Implementation of data compression, error correction (AA chain loss and within chains), homopolymer elimination, and pseudo-randomized encryption.
  • Evaluation of coding efficiency for audio, picture, and text data.

Main Results:

  • RABSR and RAHRSR systems demonstrate high coding efficiency, reaching up to 9.82 Bits/AA with error correction and compression.
  • RAHRSR system consistently outperforms RABSR system in coding efficiency across all data types.
  • Both systems effectively handle data compression, error correction, and sequence integrity.

Conclusions:

  • The developed hexadecimal polypeptide-based encoding systems offer a promising new approach for highly reliable and efficient data storage.
  • These systems overcome previous limitations, paving the way for practical polypeptide data archiving.
  • The improved coding efficiency and reliability make polypeptides a viable medium for future digital storage solutions.