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Differences in bladder neck angles between female patients with overactive bladders and healthy peers
Mehmet Yoldas1, Mehmet Zeynel Keskin2
1Tepecik Training and Research Hospital Urology Clinic, Izmir. yoldas_2297@hotmail.com.
Summary
Girls with overactive bladder show distinct bladder neck angles and ureteral orifice positioning compared to healthy girls. These anatomical differences suggest a role for bladder neck dynamics in overactive bladder development.
Area of Science:
- Pediatric Urology
- Diagnostic Imaging
- Female Lower Urinary Tract Disorders
Background:
- Overactive bladder (OAB) is a common condition in girls, impacting quality of life.
- Understanding the anatomical factors contributing to OAB pathophysiology is crucial for effective management.
Purpose of the Study:
- To investigate and compare bladder neck angles and related anatomical parameters in girls with OAB versus healthy controls.
- To identify potential ultrasonographic markers associated with OAB in pediatric females.
Main Methods:
- Transabdominal ultrasonography was employed to measure specific angles and distances in 28 girls with OAB and 40 healthy girls.
- Key measurements included anteroposterior vesical wall angle (APVA), urethroposterior vesical wall angle (UPVA), urethroanterior vesical wall angle (UAVA), bladder mucosa thickness, and ureteral orifice distance.
Main Results:
- Girls with OAB exhibited a significantly higher UAVA (135.2 ± 12.2 mm vs. 117.4 ± 14.0 mm) and a smaller UPVA (114.6 ± 19.5 mm vs. 135.3 ± 16.5 mm) compared to controls.
- The distance between ureteral orifices was markedly greater in girls with OAB (31.8 ± 8.5 mm vs. 17.0 ± 4.1 mm).
- No significant differences were observed in APVA, bladder mucosa thickness, or distance between the ureter and urethra orifice.
Conclusions:
- The observed differences in UPVA, UAVA, and ureteral orifice location suggest that bladder neck dynamics are implicated in the pathophysiology of OAB in girls.
- Transabdominal ultrasonography can reveal significant anatomical variations in girls with OAB, potentially aiding in diagnosis and understanding disease mechanisms.
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