Related Experiment Video

Updated: Jun 22, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.2K

Treatment for Opioid Use Disorder: Population Estimates - United States, 2022

Deborah Dowell, Samantha Brown, Shiromani Gyawali

    MMWR. Morbidity and Mortality Weekly Report
    |June 27, 2024
    PubMed
    Summary

    Opioid use disorder (OUD) medications significantly cut overdose deaths, yet few receive them. In 2022, only 25.1% of U.S. adults needing OUD treatment got these life-saving medications.

    More Related Videos

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    9.6K
    Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs10:13

    Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

    Published on: November 8, 2024

    2.1K

    Related Concept Videos

    Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

    Opioid Analgesics: Synthetic and Semisynthetic Opioids

    Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
    273
    Opioid Analgesics: Morphine and Other Natural Cogeners01:20

    Opioid Analgesics: Morphine and Other Natural Cogeners

    Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
    229
    Prescription, Nonprescription and Orphan Drugs01:02

    Prescription, Nonprescription and Orphan Drugs

    Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
    The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
    717
    Substance Use Disorders Affecting Sleep01:24

    Substance Use Disorders Affecting Sleep

    Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
    Understanding the concepts of physical dependence,...
    164
    Drug Abuse and Addiction: Pharmacological Phenomena01:15

    Drug Abuse and Addiction: Pharmacological Phenomena

    Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
    463
    Analgesia and Pain Management01:25

    Analgesia and Pain Management

    Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
    573