Miniaturized liquid chromatography in environmental analysis. A review
S Cortés-Bautista1, C Molins-Legua1, P Campíns-Falcó1
1Department Analytical Chemistry, University of Valencia, 46100, Burjassot, Valencia, Spain.
Journal of Chromatography. A
|June 28, 2024
Summary
Miniaturized liquid chromatography (LC) offers a greener, more sensitive environmental monitoring solution. Portable LC instruments enable in-situ analysis of emerging chemical contaminants, enhancing environmental knowledge.
Area of Science:
- Environmental Science
- Analytical Chemistry
- Green Chemistry
Background:
- Increasing chemical use leads to environmental discharge of regulated and unregulated hazardous substances.
- Emerging contaminants pose potential risks even at low concentrations.
- Conventional analytical methods face limitations in sensitivity and environmental impact.
Purpose of the Study:
- To review the environmental applications of miniaturized liquid chromatography (LC) over the past 15 years.
- To discuss advancements in portable LC instrumentation for in-situ monitoring.
- To highlight the contributions of miniaturized LC to environmental knowledge.
Main Methods:
- Review of environmental applications of miniaturized LC.
- Discussion of instrumentation, including off- and on-line pretreatment techniques.
- Analysis of chromatographic conditions and their impact on environmental analysis.
Main Results:
- Miniaturized LC presents a greener and more sensitive alternative to conventional LC.
- Portable LC instrumentation facilitates in-situ environmental monitoring.
- Significant contributions to understanding environmental chemical contamination.
Conclusions:
- Miniaturized LC is a valuable tool for environmental monitoring.
- Portable LC systems offer advantages for real-time, on-site analysis.
- Continued development of miniaturized LC enhances environmental protection strategies.
More Related Videos
Related Concept Videos
01:15High-Performance Liquid Chromatography: Types of Detectors
530
The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte...
530
00:57High-Performance Liquid Chromatography: Instrumentation
1.8K
High-performance liquid chromatography, or HPLC, is an analytical technique that separates liquid samples under high pressures. An HPLC instrument consists of glass bottles for storing solvents called mobile phase reservoirs. HPLC-grade solvents are used to maintain high purity, and the dissolved gases are removed using a degasser, such as a vacuum pumping system or sparging with helium. The solvents are then pumped into the analytical column using a screw-driven syringe or reciprocating pumps.
1.8K
01:11High-Performance Liquid Chromatography: Introduction
2.0K
High-performance liquid chromatography(HPLC), formerly referred to as High-pressure liquid chromatography, is a powerful technique used to separate, identify, and quantify components in complex mixtures. The term "high pressure" refers to using high pressure to push the liquid mobile phase through the tightly packed columns.
In HPLC, two phases play a critical role in the separation process:
In HPLC, two phases play a critical role in the separation process:
2.0K
01:30Capillary Electrophoresis: Applications
373
Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
373
01:05High-Performance Liquid Chromatography: Elution Process
455
In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...
455
01:18Supercritical Fluid Chromatography
233
Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
SFC utilizes a supercritical fluid mobile phase,...
233