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Updated: Jun 22, 2025
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Clinically Relevant Biomarkers in Connective Tissue Disease-Associated Interstitial Lung Disease
Janelle Vu Pugashetti1, Dinesh Khanna2, Ella A Kazerooni3
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan.
Abstract:
Interstitial lung disease (ILD) complicates connective tissue disease (CTD) with variable incidence and is a leading cause of death in these patients. To improve CTD-ILD outcomes, early recognition and management of ILD is critical. Blood-based and radiologic biomarkers that assist in the diagnosis CTD-ILD have long been studied. Recent studies, including -omic investigations, have also begun to identify biomarkers that may help prognosticate such patients. This review provides an overview of clinically relevant biomarkers in patients with CTD-ILD, highlighting recent advances to assist in the diagnosis and prognostication of CTD-ILD.
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