Related Experiment Video
Updated: Jun 22, 2025
09:02
Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
438
Calculated Fracture Risk among Hypertensive and Non-hypertensive Osteoporotic Women
A Mahjabin1, M T Islam, M A B Siddiq
1Dr Afsana Mahjabin, Assistant Professor, Department of Community Medicine, Monno Medical College, Manikgonj, Bangladesh;
Mymensingh Medical Journal : MMJ
|June 30, 2024
Summary
Hypertension (HTN) significantly increases the risk of hip fractures (HF) in osteoporotic women. While major osteoporotic fractures (MOF) risk was higher in hypertensive patients, only hip fracture risk showed statistical significance.
Area of Science:
- Gerontology
- Epidemiology
- Public Health
Background:
- Osteoporosis is a condition characterized by low bone mass, leading to vertebral and hip fractures.
- Hypertension (HTN) can affect bone structure, potentially increasing fracture susceptibility.
Purpose of the Study:
- To investigate the association between hypertension and the risk of osteoporotic fractures in women.
- To compare fracture risk probability between hypertensive and non-hypertensive osteoporotic female patients.
Main Methods:
- A comparative cross-sectional study involving 54 hypertensive and 34 non-hypertensive osteoporotic women.
- Data collected via face-to-face interviews using semi-structured questionnaires and checklists.
- Fracture risk assessed using the Fracture Risk Assessment Tool (FRAX) and analyzed with SPSS.
Main Results:
- Hypertensive patients aged 60-79 showed a significantly higher risk of major osteoporotic fractures (MOF) by age.
- The risk of hip fracture (HF) was significantly higher in hypertensive patients compared to non-hypertensive patients (p<0.05).
- While MOF risk was elevated in hypertensive individuals, this finding was not statistically significant (p>0.05).
Conclusions:
- Hypertension is a significant risk factor for hip fractures in osteoporotic women.
- Further research may explore the mechanisms linking hypertension and osteoporosis to refine fracture prevention strategies.
Related Concept Videos
01:29Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
01:40Bone Remodeling
38.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.3K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
125
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
125
01:31Osteoclasts in Bone Remodeling
2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K