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Updated: May 5, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
A new 3,4-dinorsteroid from the marine sponge Cliona sp
Meng-Cheng Liu1, Xiao-Jian Liao1, Xi-Wen Xing1
1Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China.
Abstract:
A new steroid, 2a-oxa-2-oxo-5β-hydroxy-3,4-dinor-24-methylcholesta-22E-ene (1), together with 10 known ones (2-11), was isolated from the marine sponge Cliona sp. The structures of these compounds were determined by the spectroscopic methods (UV, IR, MS, and NMR) and X-ray diffraction analysis. Compound 1 was the third example of 3,4-dinorsteroid with a hemiketal at C-5 that was isolated from the natural source. In addition, the antibacterial activities of these compounds were also evaluated. However, none of them exhibited significant inhibition effects.
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